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Trulicity (dulaglutide) injection logo
  • Prescribing Information
  • Instructions for Use
  • Medication Guide
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Trulicity (dulaglutide) injection logo
  • Prescribing Information
  • Instructions for Use
  • Medication Guide
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    Managing type 2 diabetes can be a challenge. Saving on your treatment shouldn’t have to be.

    Once-weekly Trulicity helps activate your body to release its own insulin. With Trulicity, you can "Activate your Within®" to help reach your A1C and blood sugar goals.

    Learn more here

    The green Truluicity Pen button

    Save on your Trulicity Pen

    The Trulicity savings card

    *Government beneficiaries excluded. See eligibility requirements, terms and conditions apply.

    You may be eligible to pay as little as $25 for your Trulicity prescription† with the Trulicity Savings Card, regardless of the dose you’ve been prescribed.

    Already have a card?

    Call 1-866-568-8942, text START to 54559, or click the button below.

    †Subject to Lilly USA, LLC’s (Lilly’s) right to terminate, rescind, revoke or amend the Trulicity Savings Card Program (“Card”) eligibility criteria and/or Card terms and conditions which may occur at Lilly’s sole discretion, without notice, and for any reason, the Card expires and savings end on 12/31/2024. Card savings are not available to patients without commercial drug insurance or who are enrolled in any state, federal, or government funded healthcare program, including, without limitation, Medicaid, Medicare, Medicare Part D, Medicare Advantage, Medigap, DoD, VA, TRICARE®/CHAMPUS, or any state prescription drug assistance program. Offer void where prohibited by law and subject to change or discontinue without notice. Card activation is required. Subject to additional terms and conditions, which can be found here .

    Trulicity support

    The Trulicity team can offer you personalized assistance in your treatment journey. That means support and resources for what you need to know—when you need to know it.

    Sign Up
    Trulicity Support

    The Trulicity pen works with the click of a button.‡

    Step 1: Uncapping the Trulicity Pen
    Step 1: Uncapping the Trulicity Pen

    Uncap the pen

    Step 2: Pack and Unlock the Trulicity Pen
    Step 2: Pack and Unlock the Trulicity Pen

    Place and unlock

    Step 3: Press and hold the Trulicity Pen
    Step 3: Press and hold the Trulicity Pen

    Press and hold

    Each dose comes in its own easy-to-use§ pen, so you can continue to have the same experience with once-weekly Trulicity, regardless of the dose you’ve been prescribed.

    ‡Be sure to read the full Instructions for Use for more information on how to deliver your Trulicity dose.
    §In a study, 94% of people who used the Trulicity Pen found it easy to use.

    How can Trulicity benefit you

    Blood sugar levels

    In studies, Trulicity has been proven to lower blood sugar levels. Trulicity starts acting in your body from the first dose.‖ In some studies, most people taking Trulicity noted better blood sugar numbers before eating in the morning (fasting blood sugar).

    ‖The first dose may start lowering blood sugar.

    A1C reduction

    Trulicity may offer lasting A1C improvements. In a study, some Trulicity users saw a significant improvement when their A1C was measured after 6 months, and it was still improved after they had been taking Trulicity for 1 year. If you do not reach your A1C goal after 6 months, talk to your healthcare provider about adjusting your medications, diet, or exercise routine.

    SAFETY SUMMARY WITH WARNINGS

    Warnings:

    Trulicity may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, trouble swallowing, hoarseness, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.

    • Do not use Trulicity if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
    • Do not use Trulicity if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
    • Do not use Trulicity if you are allergic to dulaglutide or other ingredients in Trulicity.

    Ask your healthcare provider how to recognize the serious side effects below and what to do if you think you have one:

    Inflamed pancreas (pancreatitis). Stop using Trulicity and call your healthcare provider right away if you have severe pain in your stomach area (abdomen), with or without vomiting, that will not go away. You may feel the pain from your abdomen to your back.
    Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use TRULICITY with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin.
    Signs and symptoms of low blood sugar may include dizziness or light-headedness, confusion or drowsiness, headache, blurred vision, slurred speech, fast heartbeat, sweating, hunger, shakiness, feeling jittery, weakness, anxiety, irritability, or mood changes.
    Serious allergic reactions. Stop using Trulicity and get medical help right away if you have any symptoms of a serious allergic reaction which may include swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting, or feeling dizzy, or very rapid heartbeat.
    Acute kidney injury. In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration). This may cause kidney problems to get worse.
    Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Trulicity. Tell your healthcare provider if you have stomach problems that are severe or will not go away.
    Changes in vision. Tell your healthcare provider if you have changes in your eyesight (vision) during treatment with Trulicity.
    Gallbladder problems. Gallbladder problems have happened in some people who take Trulicity. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), clay-colored stools.
    Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). Trulicity may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking Trulicity before you are scheduled to have surgery or other procedures.

    Common side effects

    The most common side effects of Trulicity include nausea, diarrhea, vomiting, abdominal pain and decreased appetite, indigestion, and fatigue.

    These are not all the possible side effects of Trulicity.

    Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch .

    Before using

    • Your healthcare provider should show you how to use Trulicity before you use it for the first time.
    • Before you use Trulicity, talk to your healthcare provider about low blood sugar and how to manage it.

    Review these questions with your healthcare provider:

    • Do you have other medical conditions, including problems with your pancreas, kidneys, liver, or stomach, or have a history of diabetic retinopathy (vision problems related to diabetes)?
    • Do you take other diabetes medicines, such as insulin or sulfonylureas?
    • Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)?
    • Are you pregnant or plan to become pregnant or breastfeeding or plan to breastfeed?
    • Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbal supplements?

    How to take

    • Read the Instructions for Use that come with Trulicity.
    • Use Trulicity exactly as your healthcare provider says.
    • Do not share your Trulicity pen, syringe, or needles with another person.
    • Do not give Trulicity to other people.
    • If you take too much Trulicity, call your healthcare provider or seek medical advice promptly.

    Learn more

    Trulicity is a prescription medicine. For more information, call 1-844-TRU-INFO (1-844-878-4636) or go to www.TRULICITY.lilly.com.

    This summary provides basic information about Trulicity but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Trulicity and how to take it. Your healthcare provider is the best person to help you decide if Trulicity is right for you.

    DG CON HL BS 11NOV2024

    Trulicity® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

    INDICATIONS

    Trulicity® (Trῡ-li-si-tee) is for adults and children 10 years of age and older with type 2 diabetes used along with diet and exercise to improve blood sugar (glucose). Trulicity is also used in adults with type 2 diabetes to reduce the risk of major cardiovascular events (problems having to do with the heart and blood vessels) such as death, heart attack, or stroke in people who have heart disease or multiple cardiovascular risk factors.

    • It is not known if Trulicity can be used in people who have had inflammation of the pancreas (pancreatitis). Trulicity is not for use in people with type 1 diabetes and is not recommended for use in people with severe stomach or intestinal problems. It is not known if Trulicity is safe and effective in children under 10 years of age.
    • Trulicity is given through an injection (needle). You take it once a week by injecting it under the skin of your stomach, thigh, or upper arm.

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      Trulicity® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

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